The Effect of Low-Dose Dexmedetomidine on Perioperative Neurocognitive Dysfunction in Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP): A Randomized, Controlled, Double-Blind Trial
Perioperative low-dose dexmedetomidine infusion with propofol in elderly ERCP patients ensures safe and effective monitored anesthesia care (MAC), reducing PND incidence by mitigating peripheral inflammation and stress responses. Long-term follow-up is needed to fully evaluate PND incidence.
Authors
- Chaolei Liu (ORCID: https://orcid.org/0000-0002-0479-7120)
- Zhangnan Sun (ORCID: https://orcid.org/0009-0001-0481-1914)
- Yini Wu
- Hong Dai (ORCID: https://orcid.org/0000-0002-7182-482X)
- Faxing Wang (ORCID: https://orcid.org/0000-0003-4636-550X)
- Jingjing Zhang (ORCID: https://orcid.org/0000-0002-4707-415X)
- Jimin Wu (ORCID: https://orcid.org/0000-0002-0979-1115)
- Yue Liu (ORCID: https://orcid.org/0009-0008-0798-9620)
- Xin Han
- Lijun Bo
- Ji Shi
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Lishui City People's Hospital (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/dddt.s470514
- Citations
- 9
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.80