Biomarker guided antibiotic stewardship in community acquired pneumonia: A randomized controlled trial
A strategy of feedback of CRP-guided and PCT-guided treatment algorithms reduced the number of days on antibiotic in the first 30 days after hospital admission in non-ICU wards for CAP. The study was not powered to determine safety of shortening duration of antibiotic treatment. (NCT01964495).
Authors
- Cornelis H. van Werkhoven (ORCID: https://orcid.org/0000-0002-0626-4635)
- Hendrik J. Prins
- Marianne Schoorl (ORCID: https://orcid.org/0000-0003-1490-7052)
- Martijn Kross
- Ruud Duijkers (ORCID: https://orcid.org/0000-0003-1376-781X)
- Nynke van der Veen
- Jan Willem van den Berg (ORCID: https://orcid.org/0000-0002-5259-0482)
- Gwendolyn M. Werkman
- Wim Boersma
- Dominic Snijders
- Marc J. M. Bonten
Institutions
- University Medical Center Utrecht (NL)
- Spaarne Ziekenhuis (NL)
- Northwest Hospital (US)
- Zaans Medisch Centrum (NL)
- Isala (NL)
- Medisch Centrum Alkmaar (NL)
- Spaarne Gasthuis (NL)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1371/journal.pone.0307193
- Citations
- 7
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71