Incidence of Medication-Related Osteonecrosis of the Jaw in Patients With Breast Cancer During a 20-Year Follow-Up: A Population-Based Multicenter Retrospective Study

MRONJ incidence in breast cancer patients with bone metastases was found to be considerably higher, especially for patients receiving denosumab, when compared with available data in the literature. Additionally, patients treated with denosumab developed MRONJ significantly earlier.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2024-08-20
DOI
https://doi.org/10.1200/jco.24.00171
Citations
27
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
7.63
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article

Incidence of Medication-Related Osteonecrosis of the Jaw in Patients With Breast Cancer During a 20-Year Follow-Up: A Population-Based Multicenter Retrospective Study

Uwe Siebert, Michael Schnallinger, Johanna Lercher, Sibylle Puntscher et al.
27 citations
Journal of Clinical Oncology
Bone health and treatments
7.63
article

Incidence of Medication-Related Osteonecrosis of the Jaw in Patients With Breast Cancer During a 20-Year Follow-Up: A Population-Based Multicenter Retrospective Study

Uwe Siebert, Michael Schnallinger, Johanna Lercher, Sibylle Puntscher, Florentina Baumgart, Emanuel Bruckmoser, Lukas Forer, Christian Marth, Claudia Iannetti, Johannes Laimer, Christine Brunner, Benjamin Walch, Agnes Pechlaner, Alice Markl, Daniel Egle, Birgit Volgger, Ewald Wöll, Miriam Emmelheinz, Marjan Arvandi, August Zabernigg, Oliver Tibor Andraschofsky, Michael Hubalek, Maria Castellan, Sebastian Schönherr
article en
27 citations

Abstract

MRONJ incidence in breast cancer patients with bone metastases was found to be considerably higher, especially for patients receiving denosumab, when compared with available data in the literature. Additionally, patients treated with denosumab developed MRONJ significantly earlier.

Journal of Clinical OncologyVol. 43(2)
Harvard University (US), Innsbruck Medical University (AT), Universität Innsbruck (AT), Massachusetts General Hospital (US), UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik (AT), Unfallkrankenhaus Salzburg (AT), University of Applied Sciences Kufstein (AT)
Good health and well-being
Openalex Percentile: Top 2%
Bone health and treatments
7.63
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