PF127/bleomycin hydrogel promotes subcutaneous extracellular matrix remodeling and fibrosis to construct personalized flaps through the TGFβ-Col signaling pathway
The PF127/BLM hydrogel promoted subcutaneous ECM remodeling and fibrosis, which aided the construction of personalized flaps through the TGFβ-Col signaling pathway, with decreased hepatic, pulmonary, and renal toxicities.
Authors
- Panfeng Wu (ORCID: https://orcid.org/0000-0003-1106-4045)
- Xiaoyang Pang (ORCID: https://orcid.org/0000-0003-1813-2039)
- Zhicheng Sun (ORCID: https://orcid.org/0000-0002-3507-6764)
- Chengxiong Huang (ORCID: https://orcid.org/0000-0001-6859-3162)
- Zheming Cao (ORCID: https://orcid.org/0000-0002-9610-305X)
- Yan Yang
- Xiao Yu (ORCID: https://orcid.org/0000-0001-8573-7092)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1080/08923973.2024.2393217
- Primary Topic
- Reconstructive Surgery and Microvascular Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hunan Province