Development of a drug delivering round window niche implant for cochlear pharmacotherapy
We developed a GP-RNI that can be used for precise inner ear drug delivery in guinea pigs, providing a reliable platform for testing the RNI's safety and efficacy, with potential implications for future clinical translation.
Authors
- Ziwen Gao (ORCID: https://orcid.org/0000-0002-9565-8838)
- Peter Erfurt
- Thomas Eickner
- Stefan Senekowitsch (ORCID: https://orcid.org/0000-0002-7251-2377)
- Chunjiang Wei
- Anne Seidlitz (ORCID: https://orcid.org/0000-0003-4493-545X)
- Martin Ulbricht
- Farnaz Matin-Mann (ORCID: https://orcid.org/0000-0002-3953-112X)
- Verena Scheper (ORCID: https://orcid.org/0000-0001-8618-8793)
- Thomas Lenarz
- Martina Knabel
- Bastian Zwick
- Norman Maggi
Institutions
- Carl Zeiss (Germany) (DE)
- Universitätsmedizin Greifswald (DE)
- Medizinische Hochschule Hannover (DE)
- Universität Greifswald (DE)
- Carl Zeiss (United States) (US)
- Eye & ENT Hospital of Fudan University (CN)
- Hearing4all (DE)
- CTI BioPharma (Italy) (IT)
- Heinrich Heine University Düsseldorf (DE)
- University of Rostock (DE)
- Deutsche Forschungsgemeinschaft (DE)
Publication Details
- Journal
- Drug Delivery
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1080/10717544.2024.2392755
- Citations
- 8
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 2.89
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- China Scholarship Council