Comprehensive laboratory assessment of lonoctocog alfa versus octocog alfa in severe haemophilia A
Lonoctocog alfa and octocog alfa showed comparable recovery and safety in vivo as well as similar impacts on TG in vitro. Observed assay discrepancies on lonoctocog alfa demonstrated variability of results also between different FVIII CSAs.
Authors
- Heiko Rühl (ORCID: https://orcid.org/0000-0003-0672-2453)
- Jens Müller (ORCID: https://orcid.org/0000-0001-7713-9631)
- Claudia Klein (ORCID: https://orcid.org/0000-0002-8230-8038)
- T. Albert (ORCID: https://orcid.org/0000-0002-0102-2792)
- Johannes Oldenburg (ORCID: https://orcid.org/0000-0002-1585-4100)
- Georg Goldmann
- Bernd Pötzsch
- Silvia Horneff
- Natascha Marquardt
Institutions
- University Hospital Bonn (DE)
Publication Details
- Journal
- Haemophilia
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1111/hae.15089
- Citations
- 1
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.45
Funders
- CSL Behring