Synaptic gene expression changes in frontotemporal dementia due to the <i>MAPT</i> 10 + 16 mutation
Our data indicate that synaptic pathology likely contributes to pathogenesis in FTDtau10 + 16 caused by the MAPT 10 + 16 mutation.
Authors
- Giles E. Hardingham (ORCID: https://orcid.org/0000-0002-7629-5314)
- Paul Baxter (ORCID: https://orcid.org/0000-0003-2142-1085)
- Owen Robert Dando (ORCID: https://orcid.org/0000-0002-6269-6408)
- Jamie McQueen (ORCID: https://orcid.org/0000-0001-7172-7504)
- Jamie Rose (ORCID: https://orcid.org/0000-0002-8110-376X)
- Jane Tulloch (ORCID: https://orcid.org/0009-0005-6975-5430)
- Robert I. McGeachan (ORCID: https://orcid.org/0000-0003-1647-8642)
- Siddharthan Chandran (ORCID: https://orcid.org/0000-0001-6827-1593)
- Declan King (ORCID: https://orcid.org/0000-0002-2434-9317)
- P. Jones (ORCID: https://orcid.org/0000-0003-0525-6323)
- Colin Smith (ORCID: https://orcid.org/0000-0002-4507-5132)
- Hannah McAlister
- Tara L. Spires‐Jones (ORCID: https://orcid.org/0000-0003-2530-0598)
- Nathan Rockley
- Xin He (ORCID: https://orcid.org/0000-0003-1753-2591)
- Adharsh Prasad
Institutions
- UK Dementia Research Institute (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- MoreBrains Cooperative (United Kingdom)
- University College London (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Neuropathology and Applied Neurobiology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1111/nan.13006
- Citations
- 4
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Wellcome Trust
- Alzheimer's Society
- Alzheimer’s Research UK
- UK Dementia Research Institute
- National Institutes of Health
- Medical Research Council