Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson’s disease: pooled analysis of patient level data from two randomized open-label studies
In these short-term trials, introducing adjunct opicapone was more effective at reducing OFF time than adding another 100 mg levodopa dose in PD patients with early signs of wearing-off.
Authors
- Joaquim José Ferreira (ORCID: https://orcid.org/0000-0003-3950-5113)
- Hyeo‐Il Ma (ORCID: https://orcid.org/0000-0001-6733-9779)
- Miguel M. Fonseca (ORCID: https://orcid.org/0000-0003-4598-670X)
- Fabrizio Stocchi (ORCID: https://orcid.org/0000-0002-5763-0033)
- Angelo Antonini (ORCID: https://orcid.org/0000-0003-1040-2807)
- Olivier Rascol (ORCID: https://orcid.org/0000-0002-1410-6397)
- Werner Poewe (ORCID: https://orcid.org/0000-0003-4367-0971)
- Beomseok Jeon (ORCID: https://orcid.org/0000-0003-2491-3544)
- José‐Francisco Rocha (ORCID: https://orcid.org/0000-0003-2611-4850)
- Guillermo Castilla‐Fernández
- Jee‐Young Lee (ORCID: https://orcid.org/0000-0002-9120-2075)
- Daniela M. Rodrigues
- Joerg Holenz
Institutions
- Bial (Portugal) (PT)
- University of Padua (IT)
- University of Lisbon (PT)
- Innsbruck Medical University (AT)
- Vita-Salute San Raffaele University (IT)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Universität Innsbruck (AT)
- Seoul National University Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Instituto Superior Politécnico do Oeste (PT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Hallym University Sacred Heart Hospital (KR)
- French Clinical Research Infrastructure Network (FR)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1007/s00415-024-12614-8
- Citations
- 7
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.58