Targeting Glioblastoma: Efficacy of Ruthenium-Based Drugs

Ruthenium compounds offer improved selectivity and fewer side effects compared to platinum-based drugs in glioblastoma treatment. Insights into their interactions with transferrin suggest targeted drug delivery, while photoactivated chemotherapy is a novel cytotoxic approach in tumor tissues.

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Publication Details

Journal
Chemical Research in Toxicology
Published
2024-08-20
DOI
https://doi.org/10.1021/acs.chemrestox.4c00188
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00

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article

Targeting Glioblastoma: Efficacy of Ruthenium-Based Drugs

Puthiyavalappil Rasin, Jebiti Haribabu, Anandaram Sreekanth, Sravan Sangeeth Surendran et al.
Chemical Research in Toxicology
Nanoparticle-Based Drug Delivery
article

Targeting Glioblastoma: Efficacy of Ruthenium-Based Drugs

Puthiyavalappil Rasin, Jebiti Haribabu, Anandaram Sreekanth, Sravan Sangeeth Surendran, Kotikalapudi Sreeramachandra Karthik
article en

Abstract

Ruthenium compounds offer improved selectivity and fewer side effects compared to platinum-based drugs in glioblastoma treatment. Insights into their interactions with transferrin suggest targeted drug delivery, while photoactivated chemotherapy is a novel cytotoxic approach in tumor tissues.

Chemical Research in ToxicologyVol. 37(9)
National Institute of Technology Tiruchirappalli (IN), University of Atacama (CL)
Ministry of Education, India, Universidad de Atacama
Good health and well-being
Openalex Percentile: Top 94%
Nanoparticle-Based Drug Delivery
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