Evaluation of a Benzodiazepine Immunoassay for Urine Drug Testing in Clinical Specimens
The Benzodiazepines II immunoassay demonstrated the greatest clinical and analytical sensitivity compared to the Benzodiazepines Plus and LDT immunoassays. The incorporation of beta-glucuronidase was crucial, as the Benzodiazepines II and LDT immunoassays demonstrated superior clinical sensitivity when compared to the Benzodiazepines Plus immunoassay that does not incorporate a beta-glucuronidase hydrolysis step.
Authors
- Adekunle Alabi (ORCID: https://orcid.org/0000-0002-3425-5955)
- Robert L. Fitzgerald (ORCID: https://orcid.org/0000-0001-6050-8525)
- Raymond T. Suhandynata (ORCID: https://orcid.org/0000-0002-4767-7639)
- Mengyuan Ge (ORCID: https://orcid.org/0000-0002-3735-377X)
- Michael J. Kelner
Institutions
- UC San Diego Health System (US)
- University of Montana (US)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1093/jalm/jfae083
- Citations
- 3
- Primary Topic
- Forensic Toxicology and Drug Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- University of California, San Diego