Single-cell RNA sequencing reveals the effects of high-fat diet on oocyte and early embryo development in female mice
HFD-induced obesity impaired ovarian morphology and oocyte function in female mice and further led to alterations in the transcriptional landscape of preimplantation embryos at different stages of HFD mice.
Authors
- Hong‐Hui Wu (ORCID: https://orcid.org/0000-0002-1381-2281)
- Qi Zhu (ORCID: https://orcid.org/0000-0001-8393-9360)
- Hongshan Ge (ORCID: https://orcid.org/0000-0001-9556-5490)
- Linglin Weng
- Xiaoqi Hong
- Na Liang (ORCID: https://orcid.org/0000-0003-2185-0007)
- Feng Li (ORCID: https://orcid.org/0000-0003-1291-5315)
- Cen Xu
- Jieyu Cai
- Huimin Ding (ORCID: https://orcid.org/0000-0002-3592-2406)
- Xia Wang (ORCID: https://orcid.org/0009-0008-6521-4938)
- Yu Xiang
- Tianyue Xu
- Mingrui Xue
- Hao Wang (ORCID: https://orcid.org/0000-0002-5270-9463)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Dalian Medical University (CN)
- Nantong University (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1186/s12958-024-01279-7
- Citations
- 8
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 8.87
Funders
- National Natural Science Foundation of China