Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy
Specific targeting of YAP with stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and VP efficiently inhibited GBM progression. This study provides a valuable drug delivery platform and creative insights for molecular targeted treatment of GBM in the future.
Authors
- Haoyue Xu
- Linbo Gu (ORCID: https://orcid.org/0009-0004-8231-7745)
- Rutong Yu (ORCID: https://orcid.org/0000-0001-8533-1973)
- Long Zhang (ORCID: https://orcid.org/0000-0002-6811-0439)
- Xiuping Zhou (ORCID: https://orcid.org/0000-0002-6663-8168)
- Ji Qi (ORCID: https://orcid.org/0000-0002-2267-532X)
- Jiahao Yu (ORCID: https://orcid.org/0009-0009-1520-4632)
- Zhongyu Ren (ORCID: https://orcid.org/0009-0004-0258-537X)
- Yan Wang (ORCID: https://orcid.org/0000-0002-8150-5486)
- Xu Wang (ORCID: https://orcid.org/0000-0002-5024-6805)
- Yining Zhang (ORCID: https://orcid.org/0000-0003-0128-1863)
- Yi Yuan (ORCID: https://orcid.org/0009-0006-6519-5314)
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1186/s12951-024-02776-y
- Citations
- 16
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 5.22
Funders
- National Natural Science Foundation of China