<scp>NRP1</scp> antagonism as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis
These findings reveal that NRP1 is upregulated in CRS and NP epithelium, and the inhibition of NRP1 may lead to a reduction in NP growth and immune cell infiltration. Our results suggest that NRP1 inhibition could be a novel possibility for treating nasal polyposis.
Authors
- Jae‐Sung Ryu (ORCID: https://orcid.org/0009-0001-7409-4535)
- Jong‐Yeup Kim (ORCID: https://orcid.org/0000-0003-1230-9307)
- Suha Lim (ORCID: https://orcid.org/0000-0002-1054-0145)
- Ji‐Hun Mo (ORCID: https://orcid.org/0000-0003-1331-364X)
- Ji-Hyeon Hwang (ORCID: https://orcid.org/0000-0002-2662-9064)
- Roza Khalmuratova (ORCID: https://orcid.org/0000-0002-8518-4034)
- Hyun‐Woo Shin (ORCID: https://orcid.org/0000-0002-4038-9992)
- Y KIM (ORCID: https://orcid.org/0000-0002-6208-6212)
Institutions
- Seoul National University (KR)
- Konyang University (KR)
- Seoul National University Hospital (KR)
- Konyang University Hospital (KR)
- Dankook University (KR)
Publication Details
- Journal
- Allergy
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1111/all.16285
- Citations
- 2
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Research Foundation of Korea