PNS Abstracts 2024

Conclusions: We have identified a novel promyelinating factor, PAK2, that acts as a critical convergence point for multiple promyelinating signaling pathways. The promyelination by PAK2 is Schwann cell-autonomous. Myelin lipids, identified as inhibitors or activators of PAK2, may be utilized to develop therapies for repairing abnormal myelin in peripheral neuropathies.

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Publication Details

Journal
Journal of the Peripheral Nervous System
Published
2024-08-01
DOI
https://doi.org/10.1111/jns.12648
Citations
4
Primary Topic
Nerve injury and regeneration
Type
article
Field-Weighted Citation Impact
1.07
Controls
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article

PNS Abstracts 2024

4 citations
Journal of the Peripheral Nervous System
Nerve injury and regeneration
1.07
article

PNS Abstracts 2024

article en
4 citations

Abstract

Conclusions: We have identified a novel promyelinating factor, PAK2, that acts as a critical convergence point for multiple promyelinating signaling pathways. The promyelination by PAK2 is Schwann cell-autonomous. Myelin lipids, identified as inhibitors or activators of PAK2, may be utilized to develop therapies for repairing abnormal myelin in peripheral neuropathies.

Journal of the Peripheral Nervous SystemVol. 29(S3)
Institute for In Vitro Sciences (US)
Openalex Percentile: Top 24%
Nerve injury and regeneration
1.07
DOIOpen Access PDFOpenAlex
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PNS Abstracts 2024 · Journal of the Peripheral Nervous System (2024) | TGRS Research Map | TGRS