Metabolomics analysis of patients with Schistosoma japonicum infection based on UPLC-MS method
This study provides evidence that GCA, GCDCA and TCDCA can potentially act as novel metabolite biomarkers to distinguish patients in different stages of S. japonicum infection. This study will contribute to the understanding of the metabolite mechanisms of the transition from chronic to advanced S. japonicum infection, although more studies are needed to validate this potential role and explore the underlying mechanisms.
Authors
- Yingzi Ming (ORCID: https://orcid.org/0000-0002-3004-4405)
- Jie Jiang (ORCID: https://orcid.org/0000-0001-6619-1936)
- Junhui Li (ORCID: https://orcid.org/0000-0001-5196-9960)
- Yu Zhang (ORCID: https://orcid.org/0000-0003-3474-422X)
- Jiang Zhu (ORCID: https://orcid.org/0009-0007-0026-3918)
- Yi Zhu
Institutions
- Central South University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Education Department of Hunan Province (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1186/s13071-024-06429-9
- Citations
- 5
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province