Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ

This work demonstrated that AfDesign can potentially be a powerful tool to facilitate the exploration of the ligand space for the purpose of targeting PDZ domains.

Authors

Emily Hendrix (ORCID: https://orcid.org/0000-0002-9248-7738)
Yi He (ORCID: https://orcid.org/0000-0002-6884-5312)
Amy O. Stevens (ORCID: https://orcid.org/0000-0001-9240-8393)
Xinyu Xia

Institutions

University of New Mexico (US)

Publication Details

Journal: Current Protein and Peptide Science
Published: 2024-08-22
DOI: https://doi.org/10.2174/0113892037316932240806102854
Citations: 2
Primary Topic: Hippo pathway signaling and YAP/TAZ
Type: article
Field-Weighted Citation Impact: 0.65

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ

Emily Hendrix, Yi He, Amy O. Stevens, Xinyu Xia

Aug 22, 2024

2 citations

Current Protein and Peptide Science

Hippo pathway signaling and YAP/TAZ

0.65

article

Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ

Emily Hendrix, Yi He, Amy O. Stevens, Xinyu Xia

August 22, 2024article en

2 citations

Abstract

This work demonstrated that AfDesign can potentially be a powerful tool to facilitate the exploration of the ligand space for the purpose of targeting PDZ domains.

Current Protein and Peptide ScienceVol. 26(10)

University of New Mexico (US)

Openalex Percentile: Top 33%

Hippo pathway signaling and YAP/TAZ

0.65

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ — Emily Hendrix, Yi He, et al. · Current Protein and Peptide Science (2024) | TGRS Research Map | TGRS