Biomarker defined infective and inflammatory asthma exacerbation phenotypes in hospitalized adults: clinical impact and phenotype stability at recurrent exacerbation
AE phenotyping in hospitalized asthma patients, based on CRP and blood eosinophils, revealed prolonged hospital stay in infective AEs and a higher risk of recurrent AE requiring hospitalization in viral versus bacterial AEs. Moreover, infective, and inflammatory AE phenotypes were rather stable at recurrent AE. Our results suggest a role for biomarker guided phenotyping of AEs of asthma.
Authors
- Asger Sverrild (ORCID: https://orcid.org/0000-0003-0625-6405)
- Ajmal Jabarkhil (ORCID: https://orcid.org/0000-0002-9214-0187)
- Muzhda Ghanizada (ORCID: https://orcid.org/0000-0001-5535-0380)
- Christian Woehlk (ORCID: https://orcid.org/0000-0003-4605-1308)
- Susanne Hansen (ORCID: https://orcid.org/0000-0002-9550-6703)
- Thérèse Lapperre (ORCID: https://orcid.org/0000-0002-5176-0101)
- Nanna Dyhre‐Petersen (ORCID: https://orcid.org/0000-0002-9794-2955)
- Celeste Porsbjerg (ORCID: https://orcid.org/0000-0003-4825-9436)
Institutions
- University of Antwerp (BE)
- Bispebjerg Hospital (DK)
- Antwerp University Hospital (BE)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1080/02770903.2024.2380510
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca
- Novartis
- Sanofi
- Teva Pharmaceutical Industries
- Chiesi España
- GlaxoSmithKline foundation
- Belgian Health Care Knowledge Centre