Patients with Morgellons disease have a lower quality of life than patients with psoriasis, atopic dermatitis and prurigo nodularis

Morgellons disease (MD) greatly affects a patient’s quality of life (QoL). Therefore, we aimed to measure the disease burden of MD on QoL and compare it with well-funded dermatological conditions, including prurigo nodularis (PN), atopic dermatitis (AD) and psoriasis. This qualitative cross-sectional survey, comprising Dermatology Life Quality Index (DLQI), Pittsburgh Sleep Quality Index (PSQI) and 5-D itch scale questionnaires, was distributed to patients with untreated MD seen at the Oregon Health and Science University Dermatology clinic from July 2022 to July 2023. When comparing mean scores across dermatological conditions, MD had significantly higher DLQI scores than PN, AD and psoriasis, and significantly higher PSQI scores than AD and psoriasis.