Open label experience of repeated OnabotulinumtoxinA injections towards the sphenopalatine ganglion in patients with chronic cluster headache and chronic migraine
Injections resulted in improvement for both groups and was maintained with repeated injections. Repeat injection after three months may be beneficial in CM. Adverse events were not uncommon, but universally transient, presumably as a result of the mechanism of action of BTA. Repeated BTA injection towards the SPG could be an effective treatment for refractory CM and CCH. Larger, randomised, placebo-controlled trials are required.
Authors
- Irina Aschehoug
- Manjit Singh Matharu (ORCID: https://orcid.org/0000-0002-4960-2294)
- Erling Tronvik (ORCID: https://orcid.org/0000-0001-6059-0151)
- Lucy Simmonds (ORCID: https://orcid.org/0000-0001-5219-2284)
- Kent Are Jamtøy (ORCID: https://orcid.org/0000-0002-4262-0908)
- Tore Wergeland Meisingset (ORCID: https://orcid.org/0000-0003-2295-123X)
- Sozaburo Hara (ORCID: https://orcid.org/0000-0003-3942-1788)
- Daniel Fossum Bratbak (ORCID: https://orcid.org/0000-0001-8483-7489)
Institutions
- Norwegian University of Science and Technology (NO)
- St Olav's University Hospital (NO)
- NORCE Research AS (NO)
- National Hospital for Neurology and Neurosurgery (GB)
- University College London (GB)
Publication Details
- Journal
- Cephalalgia
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1177/03331024241273967
- Citations
- 8
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.08