Inflammatory Biomarkers and Risk of Psychiatric Disorders

In this cohort study, inflammatory biomarkers including leukocytes, haptoglobin, CRP, and IgG were associated with a subsequent risk of psychiatric disorders, and thus might be used for high-risk population identification. The possible causal link between leukocytes and depression supports the crucial role of inflammation in the development of psychiatric disorders.

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Publication Details

Journal
JAMA Psychiatry
Published
2024-08-21
DOI
https://doi.org/10.1001/jamapsychiatry.2024.2185
Citations
70
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
11.02
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article

Inflammatory Biomarkers and Risk of Psychiatric Disorders

Unnur Anna Valdimarsdóttir, Dang Wei, Charilaos Chourpiliadis, Christina Seitz et al.
70 citations
JAMA Psychiatry
Tryptophan and brain disorders
11.02
article

Inflammatory Biomarkers and Risk of Psychiatric Disorders

Unnur Anna Valdimarsdóttir, Dang Wei, Charilaos Chourpiliadis, Christina Seitz, Huan Song, Niklas Hammar, Fang Fang, Yu Zeng
article en
70 citations

Abstract

In this cohort study, inflammatory biomarkers including leukocytes, haptoglobin, CRP, and IgG were associated with a subsequent risk of psychiatric disorders, and thus might be used for high-risk population identification. The possible causal link between leukocytes and depression supports the crucial role of inflammation in the development of psychiatric disorders.

JAMA PsychiatryVol. 81(11)
Harvard University (US), University of Iceland (IS), Sichuan University (CN), West China Medical Center of Sichuan University (CN), Karolinska Institutet (SE)
Good health and well-being
Openalex Percentile: Top 1%
Tryptophan and brain disorders
11.02
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