Assessing Psychosocial Risk and Resilience to Support Readiness for Gene Therapy in Sickle Cell Disease

Patient readiness and psychosocial factors will have tangible implications for the success of gene therapy at individual and collective levels. Health care institutions, industry, payers, policymakers, and clinicians all shoulder responsibility for ensuring that patients with SCD are adequately prepared for gene therapy and supported in ways that optimize readiness and access. Resources described here may be leveraged as a guide to support implementation of pregene therapy assessments of patient readiness and resilience in SCD.

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Publication Details

Journal
JAMA Network Open
Published
2024-08-21
DOI
https://doi.org/10.1001/jamanetworkopen.2024.29443
Citations
6
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
2.63
Controls
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article

Assessing Psychosocial Risk and Resilience to Support Readiness for Gene Therapy in Sickle Cell Disease

Victoria H. Coleman‐Cowger, Charles R. Jonassaint, Lori E. Crosby, Soumitri Sil et al.
6 citations
JAMA Network Open
Hemoglobinopathies and Related Disorders
2.63
article

Assessing Psychosocial Risk and Resilience to Support Readiness for Gene Therapy in Sickle Cell Disease

Victoria H. Coleman‐Cowger, Charles R. Jonassaint, Lori E. Crosby, Soumitri Sil, Jerlym S. Porter, Shawn M. Bediako, Cecelia Valrie, Clayton Andrews, Teonna Woolford, Steven J. Hardy, María M. Rivera
article en
6 citations

Abstract

Patient readiness and psychosocial factors will have tangible implications for the success of gene therapy at individual and collective levels. Health care institutions, industry, payers, policymakers, and clinicians all shoulder responsibility for ensuring that patients with SCD are adequately prepared for gene therapy and supported in ways that optimize readiness and access. Resources described here may be leveraged as a guide to support implementation of pregene therapy assessments of patient readiness and resilience in SCD.

JAMA Network OpenVol. 7(8)
Cincinnati Children's Hospital Medical Center (US), St. Jude Children's Research Hospital (US), Howard Hughes Medical Institute (US), Emory University (US), University of Pittsburgh (US), Virginia Commonwealth University (US), George Washington University (US), Center for Cancer and Blood Disorders (US), Aflac (United States) (US), Emmes (United States) (US), Clinical Research Consortium (US), Children's Healthcare of Atlanta (US), Ibis Reproductive Health (US), Action Network (US), University of Cincinnati Medical Center (US)
Openalex Percentile: Top 10%
Hemoglobinopathies and Related Disorders
2.63
DOIOpen Access PDFOpenAlex
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