A Cross-sectional Comparative Analysis of Eleven Population Pharmacokinetic Models for Docetaxel in Chinese Breast Cancer Patients

Three compartment PPK models may be predictive of optimal docetaxel dosage for Chinese breast cancer patients. However, for patients with impaired liver function, the choice of which model to use to predict the blood concentration of docetaxel still requires great care.

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Publication Details

Journal
Current Drug Metabolism
Published
2024-08-20
DOI
https://doi.org/10.2174/0113892002322494240816032948
Citations
1
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
0.28

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article

A Cross-sectional Comparative Analysis of Eleven Population Pharmacokinetic Models for Docetaxel in Chinese Breast Cancer Patients

Shenghui Mei, Shihui Li, Genzhu Wang, Zhongdong Li et al.
1 citations
Current Drug Metabolism
Cancer Treatment and Pharmacology
0.28
article

A Cross-sectional Comparative Analysis of Eleven Population Pharmacokinetic Models for Docetaxel in Chinese Breast Cancer Patients

Shenghui Mei, Shihui Li, Genzhu Wang, Zhongdong Li, Qiang Sun, Xiaojing Li
article en
1 citations

Abstract

Three compartment PPK models may be predictive of optimal docetaxel dosage for Chinese breast cancer patients. However, for patients with impaired liver function, the choice of which model to use to predict the blood concentration of docetaxel still requires great care.

Current Drug MetabolismVol. 25(7)
Capital Medical University (CN), Beijing Tian Tan Hospital (CN)
Capital Medical University
Good health and well-being
Openalex Percentile: Top 37%
Cancer Treatment and Pharmacology
0.28
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