Investigating the role of <i>MAB_1915</i> in intrinsic resistance to multiple drugs in <i>Mycobacterium abscessus</i>
This study reports the role of a putative fadD (MAB_1915) in innate resistance to multiple drugs by <i>M. abscessus</i>, hence identifying MAB_1915 as a valuable target and providing a baseline for further mechanistic studies and development of effective antimicrobials to check the high level of intrinsic resistance in this pathogen.
Authors
- Jingran Zhang (ORCID: https://orcid.org/0000-0001-9701-4289)
- Dmitry A. Maslov (ORCID: https://orcid.org/0000-0003-4296-5815)
- Cuiting Fang (ORCID: https://orcid.org/0000-0002-8045-3098)
- Md Shah Alam
- Shahzad Akbar Khan (ORCID: https://orcid.org/0000-0002-7431-5182)
- Xirong Tian (ORCID: https://orcid.org/0000-0003-1184-7875)
- Gift Chiwala (ORCID: https://orcid.org/0000-0002-5771-0981)
- Shuai Wang (ORCID: https://orcid.org/0000-0003-0893-2534)
- Zhiyong Liu (ORCID: https://orcid.org/0000-0002-3937-6844)
- Tianyu Zhang (ORCID: https://orcid.org/0000-0001-5647-6014)
- Yamin Gao (ORCID: https://orcid.org/0000-0002-2809-4075)
- Nanshan Zhong (ORCID: https://orcid.org/0000-0003-2274-1427)
- Buhari Yusuf (ORCID: https://orcid.org/0000-0002-4021-4519)
- Jinxing Hu (ORCID: https://orcid.org/0000-0002-1922-0498)
- Md. Mahmudul Islam (ORCID: https://orcid.org/0000-0001-7264-5180)
- H. M. Adnan Hameed (ORCID: https://orcid.org/0000-0002-8436-3508)
- Ziwen Lu
- Jie Ding
Institutions
- University of Science and Technology of China (CN)
- Anhui University (CN)
- University of Liverpool (GB)
- University of Azad Jammu and Kashmir (PK)
- Chinese Academy of Sciences (CN)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Guangzhou Institutes of Biomedicine and Health (CN)
- Hefei Institutes of Physical Science (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Chest Hospital (CN)
- University of Chinese Academy of Sciences (CN)
- University of Poonch Rawalakot
- Guangzhou Medical University (CN)
- Stanford University (US)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1128/spectrum.03974-23
- Citations
- 3
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Guangzhou Medical University
- State Key Laboratory of Respiratory Disease
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Alliance of International Science Organizations
- National Key Research and Development Program of China