Mechanism of Action of NvZhen ErXian HeJi in Ovariectomized Rats with Myocardial Infarction based on Network Pharmacology

This study reveals the potential multi-component, multi-target, and multi-pathway pharmacological effects of NZEXHJ and predicts its protection against myocardial infarction in ovariectomized rats through the PI3K Akt pathway, providing a theoretical basis for the treatment of PMCHD.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2024-08-16
DOI
https://doi.org/10.2174/0113816128308824240719093114
Primary Topic
Medicinal Plant Pharmacodynamics Research
Type
article
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article

Mechanism of Action of NvZhen ErXian HeJi in Ovariectomized Rats with Myocardial Infarction based on Network Pharmacology

Mingyang Zhu, Shuxun Guo, Xiulong Wang, Xuefang Li et al.
Current Pharmaceutical Design
Medicinal Plant Pharmacodynamics Research
article

Mechanism of Action of NvZhen ErXian HeJi in Ovariectomized Rats with Myocardial Infarction based on Network Pharmacology

Mingyang Zhu, Shuxun Guo, Xiulong Wang, Xuefang Li, Zhigang Chen, Jie Zhang, Kai Wu, Fei Lin, Linli Zhang, Desong Wen
article en

Abstract

This study reveals the potential multi-component, multi-target, and multi-pathway pharmacological effects of NZEXHJ and predicts its protection against myocardial infarction in ovariectomized rats through the PI3K Akt pathway, providing a theoretical basis for the treatment of PMCHD.

Current Pharmaceutical DesignVol. 30(39)
First Affiliated Hospital of Xinxiang Medical University (CN), Henan Medical University (CN)
Good health and well-being
Openalex Percentile: Top 83%
Medicinal Plant Pharmacodynamics Research
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