Concurrent chemoradiotherapyof different radiation doses and different irradiation fields for locally advanced thoracic esophageal squamous cell carcinoma: A randomized, multicenter, phase III clinical trial
IFI demonstrated similar treatment efficacy to ENI in CCRT of ESCC. The HD demonstrated improved PFS, but did not significantly improve OS. The dose escalation based on IFI (HD+IFI) showed better therapeutic efficacy than the current recommendation (SD+ENI) and is worth further validation.
Authors
- Hong Ge (ORCID: https://orcid.org/0000-0003-4270-2556)
- Weidong Mao (ORCID: https://orcid.org/0000-0002-9900-8058)
- Jundong Zhou (ORCID: https://orcid.org/0000-0002-3752-8728)
- Xin Yuan (ORCID: https://orcid.org/0000-0002-6375-3259)
- Kaixian Zhang
- Heyi Gong
- Gaowa Siqin
- Juan Pu (ORCID: https://orcid.org/0000-0001-7178-383X)
- Shucheng Ye
- Haiqun Lin (ORCID: https://orcid.org/0000-0002-3114-9671)
- Richard Man Kit Yu (ORCID: https://orcid.org/0000-0003-1995-2880)
- Zhongtang Wang (ORCID: https://orcid.org/0000-0003-3153-6775)
- Xiangdong Sun (ORCID: https://orcid.org/0000-0002-0051-1463)
- Shengbin Dai
- Fei Gao (ORCID: https://orcid.org/0000-0002-8026-879X)
- Yunwei Han (ORCID: https://orcid.org/0000-0002-0942-9095)
- Shaoshui Chen (ORCID: https://orcid.org/0000-0002-7134-9475)
- Dai Mingming
- Tao Zhou (ORCID: https://orcid.org/0000-0002-9265-4946)
- Minghao Li (ORCID: https://orcid.org/0000-0002-8213-0612)
- Liping Liu (ORCID: https://orcid.org/0000-0001-6356-0978)
- Guang Li (ORCID: https://orcid.org/0000-0002-3755-9479)
- Xiaomin Li (ORCID: https://orcid.org/0000-0003-0002-5112)
- Jie Li (ORCID: https://orcid.org/0000-0002-6754-9765)
- Xinchen Sun (ORCID: https://orcid.org/0000-0001-6859-7382)
- Baosheng Li (ORCID: https://orcid.org/0000-0002-5390-7269)
- Hongsheng Li (ORCID: https://orcid.org/0000-0003-1040-4108)
- Jian Zhang (ORCID: https://orcid.org/0000-0002-7337-5124)
- Lihua Dong (ORCID: https://orcid.org/0000-0002-9211-8369)
- Xianwen Zhang (ORCID: https://orcid.org/0000-0002-0616-2778)
- Anping Zheng (ORCID: https://orcid.org/0000-0001-6006-3554)
- Yongjing Yang
- Yanxing Sheng
- Xiangming Chen (ORCID: https://orcid.org/0000-0002-6397-0683)
- Wendong Gu (ORCID: https://orcid.org/0000-0001-6772-065X)
- Xiaolin Ge
- Haiwen Zhu
- Wei Huang (ORCID: https://orcid.org/0000-0003-3020-2079)
- Zhenjiang Li
- Qingsong Pang
- Xiaowei Liu (ORCID: https://orcid.org/0000-0001-8266-8650)
- Jun Wang (ORCID: https://orcid.org/0000-0002-7437-8503)
Institutions
- Hebei Medical University (CN)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Nantong University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Zhengzhou University (CN)
- Soochow University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Huaian First People’s Hospital (CN)
- Jilin Province Tumor Hospital (CN)
- Shandong Tumor Hospital (CN)
- Shanxi Provincial Cancer Hospital (CN)
- Jiangyin People's Hospital (CN)
- Second Hospital of Shandong University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Jinan Central Hospital (CN)
- Taixing People's Hospital (CN)
- Suzhou Municipal Hospital (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Inner Mongolia People's Hospital (CN)
- Yancheng Third People's Hospital (CN)
- Inner Mongolia Medical College Hospital (CN)
- Jining First People's Hospital (CN)
- Tengzhou Central People's Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
- First Hospital of China Medical University (CN)
- Henan Cancer Hospital (CN)
- First Bethune Hospital of Jilin University (CN)
- Jiangsu Province Hospital (CN)
- Taian City Central Hospital (CN)
- Liaocheng People's Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
- Anyang Tumor Hospital (CN)
- Shandong First Medical University (CN)
- Inner Mongolia Medical University (CN)
- Yangzhou University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Cancer Communications
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1002/cac2.12601
- Citations
- 10
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.73
Funders
- National Natural Science Foundation of China
- Shandong First Medical University
- Key Technology Research and Development Program of Shandong