Fecal microbiota from patients with Parkinson's disease intensifies inflammation and neurodegeneration in <scp>A53T</scp> mice
The fecal microbiota from PD patients intensifies inflammation and neurodegeneration in A53T mice. Our findings demonstrate that imbalance and dysfunction in the gut microbiome play significant roles in the development and advancement of PD.
Authors
- Weidong Le (ORCID: https://orcid.org/0000-0001-7459-2705)
- Murad Al‐Nusaif (ORCID: https://orcid.org/0000-0001-7009-7555)
- Lulu Tian (ORCID: https://orcid.org/0000-0001-5820-0337)
- Yiying Hu
- Cong Liu (ORCID: https://orcid.org/0000-0003-3425-6672)
- Panpan Wang (ORCID: https://orcid.org/0000-0003-4009-1456)
- Song Li (ORCID: https://orcid.org/0000-0003-2713-9136)
- Qian Jin (ORCID: https://orcid.org/0000-0003-3678-5455)
- Huijia Yang
- Yaping Shao (ORCID: https://orcid.org/0000-0002-8469-9036)
- Yang Ni
Institutions
- Dalian Medical University (CN)
- Chinese Academy of Sciences (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1111/cns.70003
- Citations
- 20
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China