Immune gene expression changes more during a malaria transmission season than between consecutive seasons
Our work seeks to understand how the immune response to <i>Plasmodium falciparum</i> malaria changes between infections that occur during low and high malaria transmission seasons, and highlights that immune gene expression changes more during the high transmission season. This provides important insight into the dynamics of the anti-malarial immune response that are important to characterize over these short time frames to better understand how to exploit this immune response with future vaccine efforts.
Authors
- Shannon Takala‐Harrison (ORCID: https://orcid.org/0000-0003-4674-8500)
- Bourèma Kouriba (ORCID: https://orcid.org/0000-0002-3419-5972)
- Matthew B. Laurens (ORCID: https://orcid.org/0000-0003-3874-581X)
- Emily M. Stucke (ORCID: https://orcid.org/0000-0002-8256-3290)
- Mark A. Travassos (ORCID: https://orcid.org/0000-0002-6045-3322)
- Christopher V. Plowe (ORCID: https://orcid.org/0000-0002-0045-9888)
- Drissa Coulibaly (ORCID: https://orcid.org/0000-0002-7412-0940)
- David Serre (ORCID: https://orcid.org/0000-0002-2446-9095)
- Kirsten E. Lyke (ORCID: https://orcid.org/0000-0002-4966-0830)
- Youssouf Tolo
- Amadou Niangaly (ORCID: https://orcid.org/0000-0003-3768-8446)
- Mahamadou A. Théra (ORCID: https://orcid.org/0000-0002-2679-035X)
- Abdoulaye K. Koné (ORCID: https://orcid.org/0000-0003-4101-5391)
- Karim Traoré (ORCID: https://orcid.org/0000-0002-9553-6611)
- Kieran Tebben (ORCID: https://orcid.org/0000-0001-8866-7667)
- Andrea A. Berry (ORCID: https://orcid.org/0000-0003-3140-3868)
- Salif Yirampo (ORCID: https://orcid.org/0000-0002-6510-2548)
- Ogobara K. Doumbo
- Ahmadou Dembélé
Institutions
- University of Maryland, Baltimore (US)
- Université des Sciences, des Techniques et des Technologies de Bamako (ML)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1128/spectrum.00960-24
- Citations
- 3
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 1.63