A retrospective observational study of mNGS test utilization to examine the role of diagnostic stewardship at two academic medical centers
Metagenomic next-generation sequencing (mNGS) stewardship practices remain poorly standardized. This study aims to provide actionable insights for institutions that seek to reduce the unnecessary usage of mNGS. Importantly, we highlight that clinical impact remains challenging to measure without standardized guidelines, and we provide an actual cost estimate of microbiology expenditures on individuals undergoing mNGS.
Authors
- Ryan C. Shean (ORCID: https://orcid.org/0000-0001-7855-4976)
- James Malleis
- Benjamin T. Bradley (ORCID: https://orcid.org/0000-0002-8064-9314)
- Elizabeth Garrett (ORCID: https://orcid.org/0009-0004-4066-8029)
- Joshua A. Lieberman (ORCID: https://orcid.org/0000-0002-0376-1337)
Institutions
- Pennsylvania State University (US)
- University of Washington (US)
- University of Utah (US)
- ARUP Laboratories (United States) (US)
Publication Details
- Journal
- Journal of Clinical Microbiology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1128/jcm.00605-24
- Citations
- 21
- Primary Topic
- Radiology practices and education
- Type
- article
- Field-Weighted Citation Impact
- 8.49