Microbiome time series data reveal predictable patterns of change

This project developed innovative methods to analyze gut microbiome time series data, offering fresh insights into its dynamic nature. Unlike many studies that focus on static snapshots, we found that the healthy gut microbiome is predictably stable over time, with only a small subset of bacteria showing significant changes. By identifying groups of bacteria with diverse temporal behaviors and clusters that change together, we pave the way for more effective probiotic therapies and dietary interventions, addressing the overlooked dynamic aspects of gut microbiome changes.

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Institutions

Publication Details

Journal
Microbiology Spectrum
Published
2024-08-20
DOI
https://doi.org/10.1128/spectrum.04109-23
Citations
9
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
1.87

Funders

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article

Microbiome time series data reveal predictable patterns of change

Zuzanna Karwowska, Paweł Szczerbiak, Tomasz Kościółek
9 citations
Microbiology Spectrum
Gut microbiota and health
1.87
article

Microbiome time series data reveal predictable patterns of change

Zuzanna Karwowska, Paweł Szczerbiak, Tomasz Kościółek
article en
9 citations

Abstract

This project developed innovative methods to analyze gut microbiome time series data, offering fresh insights into its dynamic nature. Unlike many studies that focus on static snapshots, we found that the healthy gut microbiome is predictably stable over time, with only a small subset of bacteria showing significant changes. By identifying groups of bacteria with diverse temporal behaviors and clusters that change together, we pave the way for more effective probiotic therapies and dietary interventions, addressing the overlooked dynamic aspects of gut microbiome changes.

Microbiology SpectrumVol. 12(10)
Silesian University of Technology (PL), Jagiellonian University (PL)
Narodowe Centrum Nauki, Narodowym Centrum Nauki
Industry, innovation and infrastructure
Openalex Percentile: Top 14%
Gut microbiota and health
1.87
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