Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline
SDD area is associated with degraded rod-mediated vision. RMDA 5° (superior retina) probes where SDD is maximal, closer to the foveal center than the rod peak at 3 to 6 mm (10.4°-20.8°) superior and the further eccentric peak of rod:cone ratio. Topographic data imply that factors in addition to rod density influence SDD formation.
Authors
- Christine A. Curcio (ORCID: https://orcid.org/0000-0001-9769-1538)
- Thomas A. Swain (ORCID: https://orcid.org/0000-0001-7039-1148)
- Kenneth R. Sloan (ORCID: https://orcid.org/0000-0002-8747-4449)
- Deepayan Kar (ORCID: https://orcid.org/0000-0003-2176-7430)
- Cynthia Owsley (ORCID: https://orcid.org/0000-0003-3424-011X)
- Mark E. Clark (ORCID: https://orcid.org/0000-0002-5660-2153)
- Lukas Goerdt (ORCID: https://orcid.org/0000-0002-6970-0940)
- Mohymina Amjad
- Gerald McGwin
Institutions
- University of Bonn (DE)
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1167/iovs.65.10.25
- Citations
- 20
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 10.77
Funders
- EyeSight Foundation of Alabama
- Research to Prevent Blindness
- Apellis Pharmaceuticals
- Bayer HealthCare
- Deutsche Forschungsgemeinschaft
- Astellas Pharma
- Heidelberg Engineering
- National Institutes of Health
- Genentech
- Novartis Pharma