Therapeutic Function of Liraglutide for Mitigation of Blast-Induced Hearing Damage: An Initial Investigation in Animal Model of Chinchilla

This study indicated that the liraglutide mitigated the blast-induced auditory injuries. In EP ears, the pre-blast administration of liraglutide reduced the severity of blast-induced acute damage in ears with EP protection, especially under G2. In animals with open ears, the effect of liraglutide on the restoration of hearing increased with time. The liraglutide potentially benefits post-blast hearing through multiple approaches with different mechanics.

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Publication Details

Journal
Military Medicine
Published
2024-08-19
DOI
https://doi.org/10.1093/milmed/usae142
Citations
2
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
Field-Weighted Citation Impact
0.72

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article

Therapeutic Function of Liraglutide for Mitigation of Blast-Induced Hearing Damage: An Initial Investigation in Animal Model of Chinchilla

Sarah Sanders, Rong Z. Gan, Paige Welch, Shangyuan Jiang
2 citations
Military Medicine
Hearing, Cochlea, Tinnitus, Genetics
0.72
article

Therapeutic Function of Liraglutide for Mitigation of Blast-Induced Hearing Damage: An Initial Investigation in Animal Model of Chinchilla

Sarah Sanders, Rong Z. Gan, Paige Welch, Shangyuan Jiang
article en
2 citations

Abstract

This study indicated that the liraglutide mitigated the blast-induced auditory injuries. In EP ears, the pre-blast administration of liraglutide reduced the severity of blast-induced acute damage in ears with EP protection, especially under G2. In animals with open ears, the effect of liraglutide on the restoration of hearing increased with time. The liraglutide potentially benefits post-blast hearing through multiple approaches with different mechanics.

Military MedicineVol. 189(Supplement_3)
University of Oklahoma (US)
U.S. Department of Defense
Openalex Percentile: Top 31%
Hearing, Cochlea, Tinnitus, Genetics
0.72
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