Assessing Survival, Distribution, and Optimal Loading Technique of Schwann Cell–Derived Exosomes Into Second-generation Axon Guidance Channels
Although only 4 second-generation AGCs were utilized, these findings indicate a potential use for SC-derived exosomes within second-generation AGCs to treat severe PNI. Future research should focus on exploring this in greater detail and in different contexts to assess the ability of SC-derived exosomes to survive at the site of injury and treat PNI.
Authors
- Joseph Yunga Tigre
- Meredith C. Costello (ORCID: https://orcid.org/0000-0001-9620-0098)
- Aisha Khan (ORCID: https://orcid.org/0000-0001-7409-9208)
- S. Shelby Burks
- Ericka A. Schaeffer (ORCID: https://orcid.org/0000-0002-7006-0178)
- Allan D. Levi (ORCID: https://orcid.org/0000-0002-0713-8497)
- Emily L. Errante (ORCID: https://orcid.org/0009-0006-7497-3173)
- Taylor Smartz
- Andrew J. Kloehn
- Yelena Pressman
Institutions
- University of Miami (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Military Medicine
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1093/milmed/usae040
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47