A four-in-one first-in-human study to assess safety, tolerability, pharmacokinetics, pharmacodynamics, and concentration-QTc relationship of HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist, in healthy men

Authors

Rong Huang (ORCID: https://orcid.org/0000-0002-2095-3883)
Quanren Wang
Kai Shen (ORCID: https://orcid.org/0009-0009-0439-635X)
Dong Xue (ORCID: https://orcid.org/0000-0002-7969-7386)
Weilin Qian (ORCID: https://orcid.org/0009-0005-9851-6869)
Zi Ye (ORCID: https://orcid.org/0009-0002-7196-6411)
Na Li (ORCID: https://orcid.org/0009-0001-9511-2384)
Lingzhi Li (ORCID: https://orcid.org/0000-0002-4308-0659)
Qi Shen (ORCID: https://orcid.org/0000-0002-5881-466X)
Zhu Luo (ORCID: https://orcid.org/0000-0003-1030-2320)
Gang Cheng (ORCID: https://orcid.org/0000-0002-8312-4599)
Manchen Bao

Institutions

Sichuan University (CN)
West China Hospital of Sichuan University (CN)
Jiangsu Hengrui Medicine (China) (CN)

Publication Details

Journal: Expert Opinion on Investigational Drugs
Published: 2024-08-19
DOI: https://doi.org/10.1080/13543784.2024.2393867
Citations: 1
Primary Topic: Hormonal Regulation and Hypertension
Type: article
Field-Weighted Citation Impact: 0.36

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article

A four-in-one first-in-human study to assess safety, tolerability, pharmacokinetics, pharmacodynamics, and concentration-QTc relationship of HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist, in healthy men

Rong Huang, Quanren Wang, Kai Shen, Dong Xue et al.

Aug 19, 2024

1 citations

Expert Opinion on Investigational Drugs

Hormonal Regulation and Hypertension

0.36

article

A four-in-one first-in-human study to assess safety, tolerability, pharmacokinetics, pharmacodynamics, and concentration-QTc relationship of HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist, in healthy men

Rong Huang, Quanren Wang, Kai Shen, Dong Xue, Weilin Qian, Zi Ye, Na Li, Lingzhi Li, Qi Shen, Zhu Luo, Gang Cheng, Manchen Bao

August 19, 2024article en

1 citations

Abstract

No abstract available for this paper.

Expert Opinion on Investigational DrugsVol. 33(10)

Sichuan University (CN), West China Hospital of Sichuan University (CN), Jiangsu Hengrui Medicine (China) (CN)

Good health and well-being

Openalex Percentile: Top 35%

Hormonal Regulation and Hypertension

0.36

DOI Source OpenAlex

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A four-in-one first-in-human study to assess safety, tolerability, pharmacokinetics, pharmacodynamics, and concentration-QTc relationship of HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist, in healthy men — Rong Huang, Quanren Wang, et al. · Expert Opinion on Investigational Drugs (2024) | TGRS Research Map | TGRS