Dysregulation of tetrahydrobiopterin metabolism in myalgic encephalomyelitis/chronic fatigue syndrome by pentose phosphate pathway
Taken together, our current research highlights that the induction of non-oxidative PPP regulates the biogenesis of biopterins contributing to ME/CFS pathogenesis.
Authors
- C. Gunnar Gottschalk (ORCID: https://orcid.org/0000-0003-4229-2542)
- Leggy A. Arnold (ORCID: https://orcid.org/0000-0003-1411-1572)
- Sarojini Bulbule (ORCID: https://orcid.org/0000-0003-2787-3058)
- Avik Roy (ORCID: https://orcid.org/0000-0003-0523-8504)
- Molly E. Drosen
- Daniel L. Peterson
Institutions
- Sierra Nevada College (US)
- University of Wisconsin–Milwaukee (US)
Publication Details
- Journal
- Journal of Central Nervous System Disease
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1177/11795735241271675
- Citations
- 5
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.91
Funders
- Solve ME/CFS Initiative
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke