Use of placental-derived mesenchymal stem cells to restore ovarian function and metabolic profile in a rat model of the polycystic ovarian syndrome
The results of this study suggest that PDMSCs are a potential treatment option for PCOS because they can effectively restore folliculogenesis and correct hormonal imbalances, lipid profiles and liver dysfunction in a rat model of PCOS. However, further research is needed to establish the safety and effectiveness of PDMSCs for treating PCOS.
Authors
- Mohsen Navari (ORCID: https://orcid.org/0000-0002-2830-9937)
- Faezeh Moradi (ORCID: https://orcid.org/0009-0007-2639-3745)
- Mansooreh Samimi (ORCID: https://orcid.org/0000-0002-5809-3612)
- Tahereh Mazoochi (ORCID: https://orcid.org/0000-0002-7070-0454)
- Mojtaba Sarvestani
- Alireza Rajabzadeh
Institutions
- Tarbiat Modares University (IR)
- Kashan University of Medical Sciences (IR)
- Torbat Heydarieh University of Medical Sciences (IR)
- Azienda USL di Bologna (IT)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1186/s12902-024-01688-0
- Citations
- 8
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 4.34
Funders
- Kashan University of Medical Sciences