Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5‐year‐old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.

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Publication Details

Journal
Australian Veterinary Journal
Published
2024-08-19
DOI
https://doi.org/10.1111/avj.13365
Citations
1
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
0.42
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article

Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

Calum Sharp, Jonathan L. Finlay, A.J. Thomas
1 citations
Australian Veterinary Journal
Electrolyte and hormonal disorders
0.42
article

Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

Calum Sharp, Jonathan L. Finlay, A.J. Thomas
article en
1 citations

Abstract

This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5‐year‐old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.

Australian Veterinary JournalVol. 102(10)
Murdoch University (AU), Western Australian Museum (AU)
Good health and well-being
Openalex Percentile: Top 34%
Electrolyte and hormonal disorders
0.42
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Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog — Calum Sharp, Jonathan L. Finlay, et al. · Australian Veterinary Journal (2024) | TGRS Research Map | TGRS