Aryliden-imidazolones as fluorogens of NanoLuc protein
We report a series of orto-substituted aryliden-imidazolones and their derivatives containing styrene moiety. These compounds can be used like ligands of NanoLuc protein. Together with NanoLuc this fluorogens can be used for genetically encoded labeling in fluorescence microscopy, as demonstrated by staining HEK293 cells.
Authors
- Михаил С. Баранов (ORCID: https://orcid.org/0000-0002-9339-7603)
- Elvira R. Zaitseva (ORCID: https://orcid.org/0000-0002-9078-1554)
- Alexander Yu. Smirnov (ORCID: https://orcid.org/0000-0002-1545-6604)
- Надежда С. Балеева (ORCID: https://orcid.org/0000-0003-2737-0733)
- Yu. А. Bogdanova
Institutions
- Pirogov Russian National Research Medical University (RU)
- Institute of Bioorganic Chemistry (BY)
Publication Details
- Journal
- Биоорганическая химия
- Published
- 2024-08-19
- DOI
- https://doi.org/10.31857/s0132342324010073
- Primary Topic
- bioluminescence and chemiluminescence research
- Type
- article
- Field-Weighted Citation Impact
- 0.00