Protection of α-Tocopherol from UV-Induced Degradation by Encapsulation into Zein Nanoparticles

Vitamin E is a fat-soluble vitamin with several forms. Among these, α-tocopherol (TOC) is preferentially absorbed and accumulated in humans. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. It is an organic chemical compound that undergoes degradation upon irradiation with UV light. To protect this bioactive chemical compound from UV light degradation, encapsulation was carried out using zein as a shell material. Due to the unique phase diagram of TOC in aqueous ethanol, the encapsulation efficiency was >99%. The size of encapsulated particles was ~300 nm or smaller, and the thickness of the shell wall was ~30 nm. The presented procedure offers the most simple and efficient encapsulation process that yields edible products. The investigation of the irradiation effect of UV on TOC revealed that the encapsulation effectively blocks UV light and prevents TOC from being degraded. The presented procedure offers an instantaneous and highly efficient encapsulation process, which yields edible products.

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Publication Details

Journal
Molecules
Published
2024-08-19
DOI
https://doi.org/10.3390/molecules29163911
Citations
6
Primary Topic
Antioxidant Activity and Oxidative Stress
Type
article
Field-Weighted Citation Impact
1.34

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article

Protection of α-Tocopherol from UV-Induced Degradation by Encapsulation into Zein Nanoparticles

Sanghoon Kim
6 citations
Molecules
Antioxidant Activity and Oxidative Stress
1.34
article

Protection of α-Tocopherol from UV-Induced Degradation by Encapsulation into Zein Nanoparticles

Sanghoon Kim
article en
6 citations

Abstract

Vitamin E is a fat-soluble vitamin with several forms. Among these, α-tocopherol (TOC) is preferentially absorbed and accumulated in humans. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. It is an organic chemical compound that undergoes degradation upon irradiation with UV light. To protect this bioactive chemical compound from UV light degradation, encapsulation was carried out using zein as a shell material. Due to the unique phase diagram of TOC in aqueous ethanol, the encapsulation efficiency was >99%. The size of encapsulated particles was ~300 nm or smaller, and the thickness of the shell wall was ~30 nm. The presented procedure offers the most simple and efficient encapsulation process that yields edible products. The investigation of the irradiation effect of UV on TOC revealed that the encapsulation effectively blocks UV light and prevents TOC from being degraded. The presented procedure offers an instantaneous and highly efficient encapsulation process, which yields edible products.

MoleculesVol. 29(16)
Agricultural Research Service (US), National Center for Agricultural Utilization Research (US)
U.S. Department of Agriculture, Agricultural Research Service
Clean water and sanitation
Openalex Percentile: Top 22%
Antioxidant Activity and Oxidative Stress
1.34
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