Comparison of Breast Magnetic Resonance Imaging and Mammography Findings in Detecting Ductal Carcinoma in situ in Preoperative Evaluation

<p>Abstract<br>Objectives: Breast cancer is the most common type of cancer in women, imaging methods have an important role in diagnosis and treatment. Ductal<br>carcinoma in situ (DCIS) accounts for approximately 30% of new breast cancer diagnoses. It was aimed to retrospectively compare the sensitivities of breast<br>magnetic resonance imaging (MRI) and mammography (MG) in detecting lesions in DCIS patients and predicting pathological subgroups of the lesion in the<br>preoperative period.<br>Methods: Preoperative MRI and MG examinations of 150 lesions diagnosed with DCIS, with an average age of 59 years, were evaluated retrospectively. In our<br>study, the sensitivities of MRI and MG were evaluated by comparing them with pathological dimensions. In addition, lesions were divided into pathological<br>subgroups and sensitivity comparisons were made between imaging methods.<br>Results: Of the 150 DCIS lesions, 30 (20%) were found solely with MG screening, 15 (10%) were found solely with MRI examination, and the remaining 105<br>(70%) patients had both MG and MRI detection. While the average size of DCIS was 1.55 cm in 135 mammograms, it was 2.10 cm in 120 MRI examinations.<br>It was statistically significantly lower in MG (p<0.05). Compared to the histopathological size of 105 cases in which lesions were found to be common in<br>both examinations, the accuracy of MRI and MG was 0.64 and 0.58, respectively. Data finds MRI more sensitive in detecting DCIS (p<0.05). Pathological<br>examinations revealed high-grade DCIS in 35 patients (23%) and low- and intermediate-grade DCIS in 115 patients (77%). In the sensitivity comparison between<br>pathological subgroups, no significant statistical difference was found between the two imaging methods (p>0.05).<br>Conclusion: MRI detects a slightly larger size than MG, it has a higher sensitivity in detecting DCIS in younger patient groups.<br>Keywords: Ductal carcinoma in situ, DCIS, magnetic resonance imaging, MRI, mammography</p>