Cerebrospinal fluid characteristics of patients presenting for evaluation of pediatric acute-neuropsychiatric syndrome
Elevation of CSF protein and albumin quotient were found in pediatric patients undergoing LP for evaluation of severe psychiatric deteriorations (PANS, AE, and other neuropsychiatric deteriorations). Further studies are warranted to investigate blood brain barrier integrity at the onset of the neuropsychiatric deterioration and explore inflammatory mechanisms.
Authors
- Margo Thienemann (ORCID: https://orcid.org/0000-0002-4952-4775)
- Elizabeth Mellins (ORCID: https://orcid.org/0000-0003-2577-139X)
- Bahare Farhadian
- Melissa A. Silverman (ORCID: https://orcid.org/0009-0001-6007-877X)
- Jennifer Frankovich (ORCID: https://orcid.org/0000-0001-7356-5617)
- Rajdeep Pooni (ORCID: https://orcid.org/0000-0002-0949-2940)
- Yuhuan Xie (ORCID: https://orcid.org/0000-0001-6716-1982)
- Wynne Zheng
- Meiqian Ma
Institutions
- Stanford Health Care (US)
- Stanford University (US)
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2024-08-19
- DOI
- https://doi.org/10.3389/fnbeh.2024.1342486
- Citations
- 4
- Primary Topic
- Infectious Encephalopathies and Encephalitis
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- U.S. Department of Health and Human Services
- North Carolina Department of Health and Human Services
- Global Lyme Alliance
- Oxnard Foundation
- National Institutes of Health
- National Institute of Mental Health
- Stanford Maternal and Child Health Research Institute