Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation
This study reveals that the treatment of endocrine disorders and ovulation disorders in PCOS with ZQLHR may be closely related to the improvement of systemic and ovarian inflammation in PCOS patients, as well as the inhibition of IL-6R, IL-1β, and LOX expression in GCs, which reemphasizes the role of reducing chronic inflammatory states in the treatment of PCOS. Moreover, this study reemphasizes the correlation between multiple inflammatory mediators and IR.
Authors
- Ruining Liang (ORCID: https://orcid.org/0000-0002-8775-4918)
- Xiaoxuan Zhan
- Shuzhen Liu (ORCID: https://orcid.org/0000-0003-4502-7816)
- Chengyi Liu (ORCID: https://orcid.org/0000-0002-8851-3104)
- Chi Chiu Wang (ORCID: https://orcid.org/0000-0002-3928-7278)
- Yixuan Zhang (ORCID: https://orcid.org/0000-0001-9781-6281)
- Xingxing Yu
- Yao Yi (ORCID: https://orcid.org/0000-0002-1678-110X)
- Yunying Ren
- Xin Li (ORCID: https://orcid.org/0009-0000-1896-9723)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Nanchang University (CN)
- Chinese University of Hong Kong (HK)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1111/aji.13918
- Citations
- 3
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Education Department of Jiangxi Province
- Jiangxi Provincial Department of Science and Technology
- Jiangxi University of Traditional Chinese Medicine