An Innovative Algorithm Based on Chaotic Maps Amalgamated with Bit-Level Permutations for Robust S-Box Construction and Its Application in Medical Image Privacy

Data security and privacy have become essential due to the increasingly advanced interconnectivity in today’s world, hence the reliance on cryptography. This paper introduces a new algorithm that uses a novel hybrid Tent–May chaotic map to generate pseudo-random numbers, as well as block encryption. We design a robust S-box by combining the Tent and May Maps, which yields a chaotic system with improved cryptographic properties. This S-box is a critical cryptographic primitive that significantly improves encryption security and leverages the strengths of both maps. The encryption process involves two key steps: block-wise substitution and permutation. First, we divide the image into 16×16 blocks, then substitute each pixel with the 8−byte key and S-box. Next, we convert the encrypted image back into vector form, reorganize it using the permutation vector based on the subgroups of S16, and finally return it to its original form. This approach greatly improves block cipher security when used, especially to protect medical images by guaranteeing their confidentiality and noninterference. Performance measures like PSNR, UACI, MSE, NCC, AD, SC, MD, and NAE prove how immune our method is to various cryptographic and statistical attacks, making it more accurate and more secure than the existing techniques.