Hypertension Severity as Quantified by Hypertension Daily Dose and Blood Pressure With Risk of Stroke in REGARDS
Among adults without prior stroke, systolic BP ≥140 mm Hg and HDD tertile ≥2 was associated with greater stroke risk. For adults with BP <140 mm Hg, stroke risk was similar despite cumulative dose of antihypertensive medications used. These findings support the practice of BP-lowering medications to mitigate stroke risk.
Authors
- Suzanne Oparil (ORCID: https://orcid.org/0000-0002-7505-2599)
- Timothy B. Plante (ORCID: https://orcid.org/0000-0001-9992-9597)
- Tyler Harkness
- Ying K. Loo (ORCID: https://orcid.org/0000-0001-7795-5102)
- Katherine Wilkinson (ORCID: https://orcid.org/0000-0001-6190-735X)
- Lillian Min (ORCID: https://orcid.org/0000-0002-4149-5092)
- Suzanne E. Judd (ORCID: https://orcid.org/0000-0001-7594-6587)
- Paul Muntner (ORCID: https://orcid.org/0000-0002-4711-5492)
- Virginia J. Howard (ORCID: https://orcid.org/0000-0003-4912-9975)
- George Howard (ORCID: https://orcid.org/0000-0002-3068-5720)
- Neil A. Zakai (ORCID: https://orcid.org/0000-0001-8824-4410)
Institutions
- University of Vermont (US)
- University of Michigan (US)
- University of Alabama at Birmingham (US)
- Geriatric Research Education and Clinical Center (US)
- Ann Arbor VA Medical Center (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1161/jaha.123.033401
- Citations
- 4
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- University of Vermont
- National Institutes of Health
- Larner College of Medicine, University of Vermont
- National Institute on Aging
- National Institute of Neurological Disorders and Stroke