Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.

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Publication Details

Journal
JAMA Neurology
Published
2024-08-19
DOI
https://doi.org/10.1001/jamaneurol.2024.2464
Citations
14
Primary Topic
Prion Diseases and Protein Misfolding
Type
article
Field-Weighted Citation Impact
3.27
Controls
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article

Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

David Westaway, Stanley B. Prusiner, Carlo Condello
14 citations
JAMA Neurology
Prion Diseases and Protein Misfolding
3.27
article

Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

David Westaway, Stanley B. Prusiner, Carlo Condello
article en
14 citations

Abstract

This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.

JAMA NeurologyVol. 81(10)
University of California, San Francisco (US)
Good health and well-being
Openalex Percentile: Top 7%
Prion Diseases and Protein Misfolding
3.27
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Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases — David Westaway, Stanley B. Prusiner, et al. · JAMA Neurology (2024) | TGRS Research Map | TGRS