Levosimendan mediates the BMP/Smad axis through upregulation of circUSP34-targeted miR-1298 to alleviate pulmonary hypertension
We have shown that Lev can be used as a therapeutic drug for PH patients, which works through the circUSP34/miR-1298/BMP/Smad axis to alleviate PH symptoms.
Authors
- Linhong Song
- Gengxu Zhou
- Qiang Meng
- Hui Wang (ORCID: https://orcid.org/0000-0001-8478-9990)
- Gang Wang (ORCID: https://orcid.org/0000-0001-9318-6251)
Institutions
- Chinese PLA General Hospital (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1186/s12931-024-02945-5
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.47