Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas

Ultra-low-dose RT emerges as an effective and well-tolerated treatment approach for OAL. Our findings support the use of 4 Gy, showcasing high complete response rates (95%) and durable disease control without significant local relapses over an average follow up of 27 months. Our results align with earlier investigations, validating the curative potential of ultra-low-dose RT and reinforcing the concept of achieving favorable outcomes with minimal intervention. This approach may potentially alleviate the burden of long-term ocular side effects associated with higher radiation doses, enhancing the overall quality of life for OAL patients.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2024-08-19
DOI
https://doi.org/10.1097/iop.0000000000002747
Citations
3
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.27
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article

Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas

Delia D. Wang, Timothy J. Sullivan, Alexandra Manta, D. Schlect
3 citations
Ophthalmic Plastic and Reconstructive Surgery
Lymphoma Diagnosis and Treatment
1.27
article

Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas

Delia D. Wang, Timothy J. Sullivan, Alexandra Manta, D. Schlect
article en
3 citations

Abstract

Ultra-low-dose RT emerges as an effective and well-tolerated treatment approach for OAL. Our findings support the use of 4 Gy, showcasing high complete response rates (95%) and durable disease control without significant local relapses over an average follow up of 27 months. Our results align with earlier investigations, validating the curative potential of ultra-low-dose RT and reinforcing the concept of achieving favorable outcomes with minimal intervention. This approach may potentially alleviate the burden of long-term ocular side effects associated with higher radiation doses, enhancing the overall quality of life for OAL patients.

Ophthalmic Plastic and Reconstructive SurgeryVol. 41(1)
Royal Women's Hospital (AU), The University of Queensland (AU), Royal Brisbane and Women's Hospital (AU), Royal Hospital for Women (AU), Queensland Eye Institute (AU), Children's Health Queensland Hospital and Health Service (AU)
Good health and well-being
Openalex Percentile: Top 20%
Lymphoma Diagnosis and Treatment
1.27
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Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas — Delia D. Wang, Timothy J. Sullivan, et al. · Ophthalmic Plastic and Reconstructive Surgery (2024) | TGRS Research Map | TGRS