Yellow nail syndrome in anti-SSA and anti-SSB positive primary Sjögren’s syndrome

Yellow nail syndrome (YNS) is a rare, acquired condition, characterised by at least two of the three clinical criteria: nail changes, respiratory tract disease and lymphoedema. Currently, the aetiology of YNS remains unknown; however, it is believed to be caused by impaired lymphatic drainage. Currently, there remain no definitive treatment options available and no prospective trials evaluating this. Management includes supportive care and symptomatic treatment. The presence of YNS has been described alongside various conditions, including autoimmune diseases, malignancies and drug exposures. To strengthen the literature on this topic, we present the case of a female patient with a history of anti-SSA and anti-SSB positive primary Sjögren's syndrome, who developed YNS in the immediate postpartum period.

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Publication Details

Journal
BMJ Case Reports
Published
2024-08-01
DOI
https://doi.org/10.1136/bcr-2024-260614
Primary Topic
Lymphatic Disorders and Treatments
Type
article
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article

Yellow nail syndrome in anti-SSA and anti-SSB positive primary Sjögren’s syndrome

Yumi Oh, Laura Jayne D'Adamo, Laurel Young
BMJ Case Reports
Lymphatic Disorders and Treatments
article

Yellow nail syndrome in anti-SSA and anti-SSB positive primary Sjögren’s syndrome

Yumi Oh, Laura Jayne D'Adamo, Laurel Young
article en

Abstract

Yellow nail syndrome (YNS) is a rare, acquired condition, characterised by at least two of the three clinical criteria: nail changes, respiratory tract disease and lymphoedema. Currently, the aetiology of YNS remains unknown; however, it is believed to be caused by impaired lymphatic drainage. Currently, there remain no definitive treatment options available and no prospective trials evaluating this. Management includes supportive care and symptomatic treatment. The presence of YNS has been described alongside various conditions, including autoimmune diseases, malignancies and drug exposures. To strengthen the literature on this topic, we present the case of a female patient with a history of anti-SSA and anti-SSB positive primary Sjögren's syndrome, who developed YNS in the immediate postpartum period.

BMJ Case ReportsVol. 17(8)
Royal Brisbane and Women's Hospital (AU), Redcliffe Hospital (AU)
Good health and well-being
Openalex Percentile: Top 75%
Lymphatic Disorders and Treatments
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