Study on antihepatocellular carcinoma effect of 6-shogaol and curcumin through network-based pharmacological and cellular assay
6-shogaol and curcumin act synergistically to alter the morphology of hepatocellular carcinoma cells, block the cell cycle in the G2/M phase, inhibit proliferation and division, and effectively promote late apoptosis. The combined action of these two components provides a theoretical basis for the further development of novel anti-liver cancer products.
Authors
- Qiuxia Jin
- Yunhe Lian
- Bimal Chitrakar (ORCID: https://orcid.org/0000-0001-7444-9255)
- Wenya Jiao
- Yaxin Sang (ORCID: https://orcid.org/0000-0003-1071-8297)
- Xianghong Wang (ORCID: https://orcid.org/0000-0003-3763-5061)
Institutions
- Hebei Agricultural University (CN)
- Chenguang Research Institute of Chemical Industry (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-19
- DOI
- https://doi.org/10.3389/fphar.2024.1367417
- Citations
- 5
- Primary Topic
- Ginger and Zingiberaceae research
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Hebei Agricultural University
- Modern Agricultural Technology Industry System of Shandong province