Population immunity to varicella in Canada: A Canadian Immunization Research Network (CIRN) study
Varicella immunity in Canada is changing. Children appear to have low population immunity, placing them at greater risk of infection and at increased risk of severe disease as they age. Our results underscore the importance of performing periodic serosurveys to monitor further population immunity changes as the proportion of vaccine-eligible birth-cohorts increases, and to continually assess the risk of outbreaks.
Authors
- Eugene Joh
- Jonathan B. Gubbay (ORCID: https://orcid.org/0000-0003-0026-3786)
- Alberto Severini
- Marc Brisson (ORCID: https://orcid.org/0000-0003-3912-6447)
- Elizabeth McLachlan
- Stephanie L. Hughes (ORCID: https://orcid.org/0000-0002-6708-3731)
- Scott A. Halperin (ORCID: https://orcid.org/0000-0003-0525-589X)
- Selma Osman
- Shelly Bolotin (ORCID: https://orcid.org/0000-0002-9100-5928)
- Sarah E. Wilson (ORCID: https://orcid.org/0000-0002-8239-0094)
- Todd F. Hatchette (ORCID: https://orcid.org/0000-0002-5377-2528)
- Jim Wright (ORCID: https://orcid.org/0000-0002-8842-2181)
- Shelley L. Deeks (ORCID: https://orcid.org/0000-0002-4055-1398)
- Carol Perez-Iratxeta
- Bouchra Serhir (ORCID: https://orcid.org/0000-0003-0735-0452)
- Natasha S. Crowcroft (ORCID: https://orcid.org/0000-0002-6761-8783)
- Brian J. Ward (ORCID: https://orcid.org/0000-0003-3251-958X)
- Sarah A. Buchan (ORCID: https://orcid.org/0000-0002-5286-8974)
Institutions
- Dalhousie University (CA)
- Statistics Canada (CA)
- Public Health Agency of Canada (CA)
- University of Toronto (CA)
- Izaak Walton Killam Health Centre (CA)
- Nova Scotia Health Authority (CA)
- Institut National de Santé Publique du Québec (CA)
- Nova Scotia Department of Health and Wellness (CA)
- Public Health Ontario (CA)
- Université Laval (CA)
- University of Manitoba (CA)
- McGill University (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1371/journal.pone.0309154
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Immunization Research Network