Comparative efficacy of the five most common traditional Chinese medicine monomers in reducing intimal hyperproliferation in arterial balloon injury models: A network meta-analysis

NMA indicates that traditional Chinese medicine monomers can effectively reduce postoperative intimal hyperproliferation in arterial balloon injury models, lowering the I/M ratio, with TPNS showing optimal efficacy. However, the research on TIIA is insufficient, and the limited sample size may affect the robustness of the results. Furthermore, the majority of research on traditional Chinese medicine monomers is currently limited to the experimental stage, lacking further clinical validation. Conducting standardized animal experiments and reporting their findings can enhance the quality of evidence from animal studies, laying the foundation for future clinical trials.

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Publication Details

Journal
Heliyon
Published
2024-08-19
DOI
https://doi.org/10.1016/j.heliyon.2024.e36327
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparative efficacy of the five most common traditional Chinese medicine monomers in reducing intimal hyperproliferation in arterial balloon injury models: A network meta-analysis

Junyan Xia, Tianshi Mao, Qun Gao, Ruli Feng et al.
Heliyon
Acute Ischemic Stroke Management
article

Comparative efficacy of the five most common traditional Chinese medicine monomers in reducing intimal hyperproliferation in arterial balloon injury models: A network meta-analysis

Junyan Xia, Tianshi Mao, Qun Gao, Ruli Feng, Long Xie, Yi Pan, Qian Lin, Zhifei Yang, Jie Wan, Xinyan Qu
article en

Abstract

NMA indicates that traditional Chinese medicine monomers can effectively reduce postoperative intimal hyperproliferation in arterial balloon injury models, lowering the I/M ratio, with TPNS showing optimal efficacy. However, the research on TIIA is insufficient, and the limited sample size may affect the robustness of the results. Furthermore, the majority of research on traditional Chinese medicine monomers is currently limited to the experimental stage, lacking further clinical validation. Conducting standardized animal experiments and reporting their findings can enhance the quality of evidence from animal studies, laying the foundation for future clinical trials.

HeliyonVol. 10(17)
Beijing University of Chinese Medicine (CN), Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 79%
Acute Ischemic Stroke Management
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